Pandemic preparedness and response is a shared responsibility involving government (local, state and federal) and the private sector. A pandemic has the potential to be a catastrophic disaster of unprecedented scale. It is estimated that the clinical disease attack rate will be 30 percent in the overall population. Rates of illness will be highest among school-aged children (about 40 percent) and decline with age. Among working adults, an average of 20 percent will become ill during a community outbreak.