Rat Mitochondria-Focused Gene Chip

The Center for the Study of Traumatic Stress is also looking at gene expression patterns present in brain tissue and in white blood cells that may contribute to the origin and neuropsychiatric phenotypes of PTSD. Using a PTSD rat model, and developing a rat mitochondria-focused gene chip,  Center scientists will subject rats to the stress protocol developed by He Li, M.D., Ph.D. to look for specific gene expression patterns. The novel diagnostic biomarkers and pharmacologic interventions described above have the potential for broad use both in military  populations (active duty, reservists and veterans) and in civilian populations exposed to traumatic events such as natural disasters, vehicle crashes, etc.